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1

The biochemical basis of hereditary fructose intolerance

Nadia Bouteldja, David J. Timson

Journal:

Journal of Inherited Metabolic Disease

Year:

2010

Language:

english

File:

PDF, 297 KB

english, 2010

2

DNA ligases in the repair and replication of DNA

David J Timson, Martin R Singleton, Dale B Wigley

Journal:

Mutation Research/DNA Repair

Year:

2000

Language:

english

File:

PDF, 1.01 MB

english, 2000

3

Adolescents who self-harm: Professional staff knowledge, attitudes and training needs

Timson, Debbie, Priest, Helena, Clark-Carter, David

Journal:

Journal of Adolescence

Year:

2012

Language:

english

File:

PDF, 142 KB

english, 2012

4

The molecular basis of galactosemia — Past, present and future

Timson, David J.

Journal:

Year:

2015

Language:

english

File:

PDF, 762 KB

english, 2015

5

NAD(P)H quinone oxidoreductase 1 (NQO1): an enzyme which needs just enough mobility, in just the right places

Pey, Angel L., Megarity, Clare F, Timson, David J

Journal:

Bioscience Reports

Year:

2018

Language:

english

File:

PDF, 757 KB

english, 2018

6

Catalytic Mechanism of Mevalonate Kinase Revisited, a QM/MM Study

McClory, James, Lin, Jun-Tang, Zhang, Jian, Timson, David J, Huang, M

Journal:

Organic & Biomolecular Chemistry

Year:

2019

File:

PDF, 880 KB

2019

7

Athletic Training Student Communication: What They Need to Talk About

Carr, W. David, Timson, Ben, Volberding, Jennifer

Journal:

Athletic Training Education Journal

Year:

2018

Language:

english

File:

PDF, 146 KB

english, 2018

8

The roles and applications of chaotropes and kosmotropes in industrial fermentation processes

Timson, David J.

Journal:

World Journal of Microbiology and Biotechnology

Year:

2020

File:

PDF, 845 KB

2020

9

Increased Promiscuity of Human Galactokinase Following Alteration of a Single Amino Acid Residue Distant from the Active Site

Helena Kristiansson, Dr. David J. Timson

Journal:

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

10

The structural and molecular biology of type I galactosemia: Enzymology of galactose 1-phosphate uridylyltransferase

Thomas J. McCorvie, David J. Timson

Journal:

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

11

Structural and molecular biology of type I galactosemia: Disease-associated mutations

Thomas J. McCorvie, David J. Timson

Journal:

Year:

2011

Language:

english

File:

PDF, 431 KB

english, 2011

12

The GAL genetic switch: visualisation of the interacting proteins by split-EGFP bimolecular fluorescence complementation

Emma Barnard, David J. Timson

Journal:

Journal of Basic Microbiology

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

13

The role of the active site residues in human galactokinase: Implications for the mechanisms of GHMP kinases

Clare F. Megarity, Meilan Huang, Claire Warnock, David J. Timson

Journal:

Bioorganic Chemistry

Year:

2011

Language:

english

File:

PDF, 658 KB

english, 2011

14

In silico identification and biochemical characterization of novel inhibitors of NQO1

Karen A. Nolan, David J. Timson, Ian J. Stratford, Richard A. Bryce

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 410 KB

english, 2006

15

Interactions between the budding yeast IQGAP homologue Iqg1p and its targets revealed by a split-EGFP bimolecular fluorescence complementation assay

Sevvel Pathmanathan, Emma Barnard, David J. Timson

Journal:

Cell Biology International

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

16

Binding of serum albumin to the anthelmintic drugs albendazole, triclabendazole and their sulphoxides

Emma Chambers, Elizabeth M. Hoey, Alan Trudgett, Ian Fairweather, David J. Timson

Journal:

Veterinary Parasitology

Year:

2010

Language:

english

File:

PDF, 285 KB

english, 2010

17

Functional analysis of disease-causing mutations in human galactokinase

David J. Timson, Richard J. Reece

Journal:

Year:

2003

Language:

english

File:

PDF, 277 KB

english, 2003

18

Sugar recognition by human galactokinase

David J Timson, Richard J Reece

Journal:

BMC Biochemistry

Year:

2003

Language:

english

File:

PDF, 1.62 MB

english, 2003

19

Liver fluke β-tubulin isotype 2 binds albendazole and is thus a probable target of this drug

Emma Chambers, Louise A. Ryan, Elizabeth M. Hoey, Alan Trudgett, Neil V. McFerran, Ian Fairweather, David J. Timson

Journal:

Parasitology Research

Year:

2010

Language:

english

File:

PDF, 316 KB

english, 2010

20

IQ motif selectivity in human IQGAP1: binding of myosin essential light chain and S100B

Sevvel Pathmanathan, Sarah F. Elliott, Sara McSwiggen, Brett Greer, Pat Harriott, G. Brent Irvine, David J. Timson

Journal:

Molecular and Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 396 KB

english, 2008

21

Interaction of prothrombin with a phospholipid surface: evidence for a membrane-induced conformational change

David F. Houston, David J. Timson

Journal:

Molecular and Cellular Biochemistry

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

22

N-acetylgalactosamine Kinase: A Naturally Promiscuous Small Molecule Kinase

Helena Kristiansson, David J. Timson

Journal:

Applied Biochemistry and Biotechnology

Year:

2012

Language:

english

File:

PDF, 276 KB

english, 2012

23

Characterization of the Saccharomyces cerevisiae galactose mutarotase/UDP-galactose 4-epimerase protein, Gal10p

Aaron Scott, David J. Timson

Journal:

FEMS Yeast Research

Year:

2007

Language:

english

File:

PDF, 161 KB

english, 2007

24

Artemisinins act through at least two targets in a yeast model

Catherine M. Moore, Elizabeth M. Hoey, Alan Trudgett, David J. Timson

Journal:

FEMS Yeast Research

Year:

2011

Language:

english

File:

PDF, 220 KB

english, 2011

25

Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase

David J. Timson

Journal:

Year:

2005

Language:

english

File:

PDF, 315 KB

english, 2005

26

Functional domains of the human epididymal protease inhibitor, eppin

Maelíosa T. C. McCrudden, Tim R. Dafforn, David F. Houston, Philip T. Turkington, David J. Timson

Journal:

Year:

2008

Language:

english

File:

PDF, 314 KB

english, 2008

27

The structural and molecular biology of type III galactosemia

David J. Timson

Journal:

Year:

2006

Language:

english

File:

PDF, 426 KB

english, 2006

28

Coumarin-Based Inhibitors of Human NAD(P)H:Quinone Oxidoreductase-1. Identification, Structure–Activity, Off-Target Effects and In Vitro Human Pancreatic Cancer Toxicity

Nolan, Karen A., Zhao, He, Faulder, Paul F., Frenkel, A. David, Timson, David J., Siegel, David, Ross, David, Burke Jr., Terrence R., Stratford, Ian J., Bryce, Richard A.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 1.16 MB

english, 2007

29

A ligand predication tool based on modeling and reasoning with imprecise probabilistic knowledge

Weiru Liu, Anbu Yue, David J. Timson

Journal:

Computer Methods and Programs in Biomedicine

Year:

2010

Language:

english

File:

PDF, 822 KB

english, 2010

30

Fasciola hepatica expresses multiple α- and β-tubulin isotypes

Louise A. Ryan, Elizabeth Hoey, Alan Trudgett, Ian Fairweather, Marc Fuchs, Mark W. Robinson, Emma Chambers, David J. Timson, Eimear Ryan, Theresa Feltwell, Al Ivens, Geoffrey Bentley, David Johnston

Journal:

Molecular and Biochemical Parasitology

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

31

Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease

Carla M. Yuede, Scott D. Zimmerman, Hongxin Dong, Matthew J. Kling, Adam W. Bero, David M. Holtzman, Benjamin F. Timson, John G. Csernansky

Journal:

Neurobiology of Disease

Year:

2009

Language:

english

File:

PDF, 740 KB

english, 2009

32

Structure of the adenylation domain of an NAD+-dependent DNA ligase

Martin R Singleton, Kjell Håkansson, David J Timson, Dale B Wigley

Journal:

Year:

1999

Language:

english

File:

PDF, 776 KB

english, 1999

33

The N-terminus of A1-type myosin essential light chains binds actin and modulates myosin motor function

David J. Timson, Hylary R. Trayer, Ian P. Trayer

Journal:

Year:

1998

Language:

english

File:

PDF, 487 KB

english, 1998

34

The Molecular Dynamics of Trypanosoma brucei UDP-Galactose 4′-Epimerase: A Drug Target for African Sleeping Sickness

Aaron J. Friedman, Jacob D. Durrant, Levi C. T. Pierce, Thomas J. McCorvie, David J. Timson, J. Andrew McCammon

Journal:

Chemical Biology & Drug Design

Year:

2012

Language:

english

File:

PDF, 3.11 MB

english, 2012

35

Hydrophobic substances induce water stress in microbial cells

Prashanth Bhaganna, Rita J. M. Volkers, Andrew N. W. Bell, Kathrin Kluge, David J. Timson, John W. McGrath, Harald J. Ruijssenaars, John E. Hallsworth

Journal:

Microbial Biotechnology

Year:

2010

Language:

english

File:

PDF, 982 KB

english, 2010

36

Functional domains of an NAD+-dependent DNA ligase

David J Timson, Dale B Wigley

Journal:

Journal of Molecular Biology

Year:

1999

Language:

english

File:

PDF, 264 KB

english, 1999

37

In vivo and in vitro function of human UDP-galactose 4′-epimerase variants

Thomas J. McCorvie, Jamie Wasilenko, Ying Liu, Judith L. Fridovich-Keil, David J. Timson

Journal:

Year:

2011

Language:

english

File:

PDF, 686 KB

english, 2011

38

Detection and localisation of protein–protein interactions in Saccharomyces cerevisiae using a split-GFP method

Emma Barnard, Neil V. McFerran, Alan Trudgett, John Nelson, David J. Timson

Journal:

Fungal Genetics and Biology

Year:

2008

Language:

english

File:

PDF, 481 KB

english, 2008

39

Plume characteristics and dynamics of UV and IR laser-desorbed oligonucleotides

Tony L. Merrigan, David J. Timson, C. Adam Hunniford, Martin Catney, Robert W. McCullough

Journal:

International Journal of Biological Macromolecules

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

40

Substrate Specificity and Mechanism from the Structure of Pyrococcus furiosus Galactokinase

Andrew Hartley, Steven E. Glynn, Vladimir Barynin, Patrick J. Baker, Svetlana E. Sedelnikova, Corné Verhees, Daniel de Geus, John van der Oost, David J. Timson, Richard J. Reece, David W. Rice

Journal:

Journal of Molecular Biology

Year:

2004

Language:

english

File:

PDF, 3.44 MB

english, 2004

41

Identification and characterisation of human aldose 1-epimerase

David J. Timson, Richard J. Reece

Journal:

Year:

2003

Language:

english

File:

PDF, 521 KB

english, 2003

42

The rôle of the proline-rich region in A1-type myosin essential light chains: implications for information transmission in the actomyosin complex

David J Timson, Ian P Trayer

Journal:

Year:

1997

Language:

english

File:

PDF, 1.38 MB

english, 1997

43

Kinetic analysis of yeast galactokinase: implications for transcriptional activation of the GAL genes

David J. Timson, Richard J. Reece

Journal:

Year:

2002

Language:

english

File:

PDF, 141 KB

english, 2002

44

Fine tuning the myosin motor: the role of the essential light chain in striated muscle myosin

David J. Timson

Journal:

Year:

2003

Language:

english

File:

PDF, 315 KB

english, 2003

45

IQ-motif peptides as novel anti-microbial agents

McLean, Denise T.F., Lundy, Fionnuala T., Timson, David J.

Journal:

Year:

2013

Language:

english

File:

PDF, 709 KB

english, 2013

46

A plasma membrane Ca2+-ATPase (PMCA) from the liver fluke, Fasciola hepatica

Catherine M. Moore, Elizabeth M. Hoey, Alan Trudgett, David J. Timson

Journal:

International Journal for Parasitology

Year:

2012

Language:

english

File:

PDF, 1.09 MB

english, 2012

47

Nucleotide sequence, heterologous expression and novel purification of DNA ligase from Bacillus stearothermophilus

James A Brannigan, Stephen R Ashford, Aidan J Doherty, David J Timson, Dale B Wigley

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1999

Language:

english

File:

PDF, 506 KB

english, 1999

48

FhCaBP4: aFasciola hepaticacalcium-binding protein with EF-hand and dynein light chain domains

Rebecca Orr, Ruth Kinkead, Richard Newman, Lindsay Anderson, Elizabeth M. Hoey, Alan Trudgett, David J. Timson

Journal:

Parasitology Research

Year:

2012

Language:

english

File:

PDF, 376 KB

english, 2012

49

A calcium-dependent interaction between calmodulin and the calponin homology domain of human IQGAP1

Andrews, William J., Bradley, Conor A., Hamilton, Elaine, Daly, Clare, Mallon, Thérèse, Timson, David J.

Journal:

Molecular and Cellular Biochemistry

Year:

2012

Language:

english

File:

PDF, 375 KB

english, 2012

50

Altered cofactor binding affects stability and activity of human UDP-galactose 4′-epimerase: Implications for type III galactosemia

Thomas J. McCorvie, Ying Liu, Andrew Frazer, Tyler J. Gleason, Judith L. Fridovich-Keil, David J. Timson

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

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